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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7510 | Leucylarginylproline | RAAS | |
Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM). | |||
T1484 | Perindoprilat | Perindoprilate | RAAS , MRP , AChR |
Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor. | |||
T1145 | Diminazene Aceturate | Others , Serine Protease , Parasite | |
Diminazene is a trypanocidal agent. | |||
T1489 | Fosinopril sodium | SQ28555 | RAAS |
Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat. | |||
T13865 | Resorcinolnaphthalein | RAAS | |
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM). | |||
T16116 | MLN-4760 | RAAS | |
MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypept... | |||
T7686 | Ramiprilat | RAAS | |
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T7714 | Temocapil | Tyrosinase | |
Temocapril is an inhibitor of tyrosine kinase. | |||
TP1828 | N-Acetyl-Ser-Asp-Lys-Pro | RAAS | |
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit... | |||
T1605 | Enalapril | MK-421 | RAAS , MRP |
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T7339 | Angiotensin (1-7) | Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO | RAAS , Endogenous Metabolite |
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.65 μM) with vasodilator and antiproliferative activiti... | |||
T7808 | Alacepril | Cetapril,DU-1219 | RAAS |
Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive | |||
T1645 | Ramipril | HOE-498,Tritace,Altace,Carasel | Apoptosis , RAAS |
Ramipril (Altace) is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat. | |||
T5030 | Zofenopril calcium | SQ26991,Zofenopril (calcium) | RAAS , Reactive Oxygen Species |
Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound z... | |||
T0180 | Benazepril hydrochloride | CGS 14824A HCl,Benazepril HCl,CGS14824A | RAAS |
Benazepril hydrochloride (CGS 14824A HCl) is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril hydrochloride is associated with a low rate of transient serum aminotra... | |||
T2679 | BMS-265246 | BMS265246 | CDK |
BMS-265246 is a potent and selective CDK1/2 inhibitor. | |||
T6340 | Enalaprilat Dihydrate | MK-422,MK-422 Dihydrate | RAAS , Autophagy |
Enalaprilat Dihydrate (MK-422 Dihydrate) (IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor. | |||
T6698 | Temocapril hydrochloride | CS-622 HCl,Acecol,Temocapril HCl,CS-622 | RAAS |
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension. | |||
T0706 | Lisinopril dihydrate | Lisinopril,Renacor,MK-521 (dihydrate) | RAAS , MRP |
Lisinopril dihydrate (MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T5329 | Trandolapril | Angiotensin-converting Enzyme (ACE) | |
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat. | |||
T3281 | Delapril hydrochloride | indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317 | RAAS |
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme... | |||
T6542 | Imidapril hydrochloride | Novaloc,Imidapril HCl,Tanapril,TA-6366 | RAAS |
Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. | |||
T0805 | Quinapril hydrochloride | CI-906,PD-109452-2,Quinapril HCl | RAAS |
Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril hydrochloride is associated with a low rate of transie... | |||
T1462 | Captopril | SQ 14225,SQ-14534,SA333 | RAAS |
Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure. | |||
T1484L | Perindopril erbumine | S9490-3,Perindopril tert-butylamine salt | Apoptosis , RAAS , MRP |
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril er... | |||
T6595 | Moexipril hydrochloride | Moexipril HCl,RS-10085,SPM 925,CI-925 | Apoptosis , RAAS |
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure. | |||
T6486 | Enalapril Maleate | MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate | RAAS |
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy. | |||
T6444 | Cilazapril Monohydrate | Ro 31-2848 monohydrate,Justor | RAAS |
Cilazapril Monohydrate (Justor) is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. | |||
T25832 | Moveltipril | Moveltipril calcium,MC-838,Altiopril calcium | RAAS |
Moveltipril (Moveltipril calcium) is a potent angiotensin-converting enzyme (ACE) inhibitor.Moveltipril is converted to captopril in the body for action. | |||
T25226 | Ceronapril | Ceronaprilum,SQ 29852,SQ-29852,SQ29852 | RAAS |
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension. | |||
T20689 | Temocaprilat | RNH-5139,RS-5139,RNH 5139,RNH5139,RS5139,RS 5139 | Angiotensin-converting Enzyme (ACE) |
Temocaprilat (RS5139) is an Angiotensin-converting Enzyme (ACE) inhibitor. Temocaprilat is effectively excreted in bile via cMOAT that is deficient in EHBR and that many of other ACE inhibitors have low affinity for cMOA... | |||
T24906L | Tuna AI acetate | Angiotensin-converting Enzyme (ACE) | |
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle. | |||
TP1750L | H-Ile-Pro-Pro-OH acetate | H-Ile-Pro-Pro-OH acetate(26001-32-1 free base) | Angiotensin-converting Enzyme (ACE) |
H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides. | |||
T7354 | H-Val-Pro-Pro-OH | RAAS | |
H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM). | |||
TP1920L1 | Acein acetate | RAAS | |
Acein acetate is a high-affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Concentrations up to 500 nM had no significant effect on ACE enzyme activity. Enhanced NMDA + D-serine-induced dopamine release ... | |||
TP1682L | Abz-FR-K(Dnp)-P-OH acetate(500799-61-1 free base) | Others | |
Abz-FR-K(Dnp)-P-OH acetate is an excellent angiotensin I-converting enzyme (ACE) substrate with a Km value of 4.0 μM and a kcat value of 210s-1. | |||
TP1295 | Angiotensin I (human, mouse, rat) | Angiotensin 1 Human | Others |
Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).Angiotensin is a peptide hormone that causes vasoconstriction and an in... | |||
TP1404L | Hemorphin-7 acetate(152685-85-3 free base) | Opioid Receptor | |
Hemorphin-7 acetate is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemorphin peptides exhibits antinociceptive and antihypertensive activities, activating opioid receptors an... | |||
T25254 | CL 242817 | CL242817,CL-242817 | |
CL 242817 is an inhibitor of angiotensin converting enzyme (ACE). | |||
T12198 | NCX899 | Others | |
NCX899 shows inhibitory activity against angiotensin-converting enzyme (ACE) activity. | |||
T13274 | Utibapril | FPL 63547 | Others |
Utibapril is an inhibitor of angiotensin-converting enzyme (ACE) with antihypertensive activities. | |||
T20921 | Benazepril | CGS-14824-A | |
Benazepril inhibits the activity of circulating angiotensin-converting enzyme (ACE) in horses. | |||
T12704 | Rentiapril | SA-446 | RAAS |
Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity. | |||
T27608 | Indolapril hydrochloride | REV 6000A(SS),CI-907,CI 907,CI907,Indolapril HCl | |
Indolapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T71028 | Lisinopril, epsilon-biotinamidocaproyl- | ||
Lisinopril, epsilon-biotinamidocaproyl- is an angiotensin converting enzyme (ACE) inhibitor. | |||
T28584 | Ro 31-8472 | Ro-31-8472,Ro 318472 | |
Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat. | |||
T70698 | MDL-100173 | ||
MDL-100173 is a dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitor. | |||
T62377 | Zofenopril | ||
Zofenopril is an angiotensin-converting enzyme (ACE) inhibitor (IC50: 81 μM). | |||
T11194 | Enalaprilat D5 | MK-422 D5 | Others |
Enalaprilat D5 is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor. | |||
T11192 | Enalapril D5 maleate | MK-421 D5 maleate | Others |
Enalapril D5 maleate is deuterium labeled Enalapril, which is an angiotensin converting enzyme (ACE) inhibitor. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
T8270 | Deserpidine | Harmonyl | RAAS |
Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive propertie... | |||
T13299 | Vicenin 3 | RAAS | |
Vicenin 3 is an inhibitor of angiotensin-converting enzyme (ACE; IC50: 46.91 μM) from the aerial parts of Desmodium styracifolium. | |||
T5796 | Plantainoside D | Isoplantamajoside | RAAS , PKC |
Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it ... | |||
T21418 | Lisinopril | Linopril,Zestril,Prinivil,Lisipril | RAAS |
Lisinopril (Prinivil), the angiotensin-converting enzyme (ACE) inhibitor, is used primarily in the treatment of high heart failure, blood pressure, and heart attacks. It is also used for preventing eye and kidney complic... | |||
T3851 | Vicenin 2 | Vicenin -2 | RAAS |
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,... | |||
T3753 | Sinapinic Acid | Sinapic acid,Synapoic acid | Apoptosis , RAAS , Reactive Oxygen Species , HDAC |
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap... | |||
T6627 | Phosphoramidon Disodium | Phosphoramidon Disodium Salt | RAAS , Neprilysin , Others |
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. | |||
TN2295 | Vicenin-1 | Vicenin -1 | Antioxidant , Angiotensin-converting Enzyme (ACE) |
Vicenin-1 (Vicenin -1) is a flavonoid glycoside isolated from the seeds of the leguminous plant fenugreek with potent anti-inflammatory and antioxidant activity, inhibiting angiotensin-converting enzyme (ACE). | |||
T38481 | Camellianin B | ||
Camellianin B, a flavonoid compound and metabolite of Camellianin A, exhibits antioxidant properties and acts as an angiotensin converting enzyme (ACE) inhibitor. | |||
TN5645 | Isomartynoside | ||
Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity. | |||
TN4860 | Pueroside B | COX , PPAR | |
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A rece... | |||
T79958 | Isocrenatoside | Angiotensin-converting Enzyme (ACE) | |
Isocrenatoside (compound 6), a cyclic octapeptide derived from the ethanolic extract of Microtoena prainiana stems, functions as an angiotensin-converting enzyme (ACE) inhibitor. Research demonstrates that at a concentra... | |||
TN4431 | Leucosceptoside A | RAAS , PKC | |
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows ... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPJ-00386 | ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated | Human | Human Cells |
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypept... | |||
TMPH-03081 | ACE2 Protein, Paguma larvata, Recombinant (hFc) | Paguma larvata | HEK293 |
Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin ... | |||
TMPY-02574 | Chymase 1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II sys... | |||
TMPY-03830 | ACE2/ACEH Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-03561 | ACE2/ACEH Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-02207 | ACE2/ACEH Protein, Rat, Recombinant (His) | Rat | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-00655 | ACE2/ACEH Protein, Human, Recombinant (hFc) | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-05725 | ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Baculovirus-Insect Cells |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-05266 | ACE2/ACEH Protein, Human, Recombinant (His) | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-01839 | ACE2/ACEH Protein, Mouse, Recombinant (His & hFc) | Mouse | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-01838 | ACE2/ACEH Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-05696 | ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-04312 | ACE2/ACEH Protein, Human, Recombinant (mFc) | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-06334 | ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 |
Angiotensin-converting enzyme 2 (ACE2), a first homolog of ACE, regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Accumulating evidence in recent years has demonstrated a physiological and pa... | |||
TMPY-04501 | Angiotensinogen Protein, Rat, Recombinant (His) | Rat | HEK293 |
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti... | |||
TMPY-02232 | Angiotensinogen Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti... | |||
TMPY-01232 | Angiotensinogen Protein, Human, Recombinant (His) | Human | HEK293 |
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti... |